Everything You Should Know About CBDA

CBDA Cannabinoid – The Complete Guide

CBD versus CBDA: You’ve probably heard about CBD. But what about CBDA? What exactly is CBDA? Are there any CBDA advantages? What is the finest CBDA oil available? CBD products are most likely on shop shelves near you. CBD is becoming increasingly popular. CBDA cannabinoid and other cannabinoids are already making their way onto the health supplement market.

CBDA is not a misspelling. Also, CBDA and CBD are not interchangeable. They are distinct compounds, despite their close closeness.

In this essay, we’ll go deep into CBDA and teach you all you need to know about CBDA and CBD before purchasing a bottle. We will discuss CBDA advantages as well as CBD benefits and other topics.

But, before we get into what CBDA cannabinoid is, let’s go through the more well-known cannabinoids, THC and CBD.

Cannabinoids: A Quick Overview

To get to CBDA, let’s start with the most well-known cannabinoids in the health and wellness world: CBD and THC. Actually, let’s take it a step farther!

What Exactly Is a Cannabinoid?

A cannabinoid is an organic molecule present in the cannabis plant. Over 110 cannabinoids are now recognized, with more expected to be discovered as research continues. Cannabis is indeed a magnificent plant!

These cannabinoids are responsible for the effects of marijuana (THC), CBD, CBDA, and other cannabinoid products that consumers have grown to appreciate. But how exactly?

Well, cannabinoids interact with the human body via receptors in the endocannabinoid system, also known as the ECS. The ECS is a relatively new system that governs our homeostasis and health functions such as mood, anxiety, stress, sleep, inflammation, pain, and more. There are two major receptors in this ECS – CB1 and CB2.

Let’s Learn More About CB1 and CB2

While CB1 receptors predominantly interact with the brain and neurological system, CB2 receptors largely connect with our immune system. Our bodies naturally manufacture endocannabinoids, but once they’re out of balance, we experience anxiety, stress, and other mood problems, as well as difficulty sleeping.

THC, CBD, CBDA, and other cannabinoids derived from the cannabis plant can imitate our bodies’ natural endocannabinoids. To create their numerous potential health advantages, they connect to our CB1 and CB2 receptors.

Cannabinoids provide varied advantages because they each have distinct properties and attach to our receptors in different ways. Cannabinoids frequently perform even better when combined with other cannabinoids and chemicals, a phenomenon known as the entourage effect.

Why are THC and CBD becoming more popular?

CBDA research is still in its early phases, mostly because more is known about them, and it is more difficult to extract CBDA than THC or CBD (more on that later).

THC has been used medicinally and recreationally for ages, but CBD has only lately emerged.

Despite its current popularity and rise, CBD still has a stigma. This is because of its connection to THC and marijuana. Despite its same origin, CBD and THC have distinct roles.

The intoxicating ingredient present in Cannabis Sativa is THC, or tetrahydrocannabinol. In a nutshell, THC is the psychoactive molecule. THC is most commonly absorbed via smoking THC-rich marijuana strains, but it is also available as oils, tinctures, capsules or softgels, and sweets such as a CBD gummy.

About The CBD

CBD, or cannabidiol, is found in the same plant but is non-psychoactive, which means it will not get you high while providing medicinal advantages. As a result, it has gained popularity. CBD is frequently derived from CBD-rich cannabis cultivars, such as hemp. Oils, tinctures, supplements, extracts, food and beverage items, gummies, and almost everything include it.

CBD products with a high THC concentration are derived from marijuana plants, but the majority of CBD products on the market (and the only ones formally permitted by the FDA) have a THC content of 0.3 percent or less.

So, What Exactly Is CBDA?

Cannabigerolic acid (CBGa), the mother of all cannabinoids, is the source of all cannabinoids in cannabis and hemp.

The CBGa is subsequently converted by plant enzymes into a mixture of three primary cannabinoid precursor compounds: tetrahydrocannabinolic acid (THCA), cannabichromenic acid (CBCA), and cannabidiolic acid (CBDA). The combination will be determined by the specific cannabis strain from which they are developed.

CBDA is a non-psychoactive substance that acts as a precursor to CBD. To be more explicit, CBDA is decarboxylated to produce CBD, which means it is heated. This can happen quickly if the plant material is smoked or vaped, or slowly if it is left to dry in the sun or even at room temperature.

As a result, cannabidiolic acid can be thought of as raw CBD. CBDA is most commonly found in live or raw hemp plants that have been cultivated for high CBD levels.

Cannabidiolic acid (CBD) is often ingested, however it can also be useful in its unprocessed form. CBDA oil is available as tinctures, raw cannabis juice, topical creams, and raw CBDA oil.

CBDA has received far less public notice and is seen much less on the market to date. The raw juicing cannabis movement, on the other hand, is pushing CBDA to the forefront. People are curious about the distinctions between CBD and CBDA and if CBDA is superior than CBD.

The Distinctions Between CBDA and CBD

The primary distinction, as previously stated, is that CBDA is indeed a precursor to CBD. CBD is produced by heating CBDA or raw CBD.

While CBDA research is still in its early phases, we do know that it and CBD have several commonalities.

For starters, they are both non-psychoactive, which means they will not get users high or stoned. This is due to the fact that CBD and CBDA do not directly interact with our endocannabinoid receptors.

Second, it is assumed that CBD and CBDA produce their distinctive effects by activating our 5-HT1A serotonin receptors. You’ve probably heard of serotonin, which is a critical chemical in our brains that regulates our mood, sleep, anxiety, and even sickness.

CBD has been shown to alleviate symptoms of anxiety, melancholy, inflammation, and even a rare form of pediatric epilepsy. CBD is included in a wide range of health supplements due to its flexibility and the fact that it has received far more research than CBDA.

The CBDA Research

Meanwhile, CBDA is still in its early phases of development, but it shows just as much, if not more, potential than CBD. One research, for example, discovered that CBDA has antidepressant effects on rats at levels 10 to 100 times lower than CBD.

This is because CBDA interacts with serotonin receptors. For the same reason, CBDA is being studied as an anti-nausea medication, with one study indicating CBDA to be more effective than CBD at relieving nausea.

Furthermore, on January 12, 2022, a story was published on Forbes.com. “Study Finds Cannabis Compounds Prevent Infection By Covid-19 Virus” shares some new, interesting CBDA findings and mentions – “…researchers discovered that two cannabinoid acids commonly found in hemp varietals of cannabis, cannabigerolic acid, or CBGA, and cannabidiolic acid, also known as CBDA, can bind to the spirilla virus.” The chemicals, by binding to the spike protein, can block the virus from entering cells and causing infection, thus opening up new paths for disease prevention and treatment.” The article continues, “Orally accessible and with a long history of safe human usage, these cannabinoids, individually or in hemp extracts, have the potential to prevent as well as cure SARS-CoV-2 infection,” the researchers concluded in the study’s abstract.

What Are the Potential Advantages?

Because CBDA and other acidic variants of cannabinoids are not thought to be pharmacologically active, cannabinoids like THC and CBD have received far more attention than CBDA. This indicates that they do not have the same effect on the ECS as their decarboxylated counterparts. As a result, most study has concentrated on CBD rather than CBDA.

CBDA Most Recent Research

However, a new study indicates that raw CBDA oil has its own distinct potential. CBDA has been shown in one research to be an effective anti-inflammatory drug.

CBDA was shown to be more effective than THC at blocking COX-2, an enzyme released when there is inflammation, in this study. The same study discovered that the acidic component of CBDA is critical to its capacity to inhibit COX-2.

Another study discovered that CBDA was 1,000 times more effective than CBD for anti-nausea and anti-anxiety effects. CBDA had “much better effectiveness in inhibiting vomiting in shrews and nausea in rats” as compared to CBD in this animal model research.

One of the issues with CBDA cannabinoid in terms of possible medicinal applications is that it is an unstable molecule. This is clear when you examine how slowly it decarboxylates even at room temperature. Dr. Raphael Mechoulam, the cannabis scientist who originally synthesized THC and CBD, said at the 2019 CannMed conference that his research team identified a method to convert unstable CBDA into a more stable chemical.

Furthermore, CBDA appears to share the majority of the advantages that CBD consumers desire, such as anti-anxiety characteristics and others.

Is CBDA more effective than CBD?

It’s too early to say until we get real data from human testing! However, preliminary study shows that raw CBD oil may be equally, if not more, helpful in treating conditions such as depression, nausea, and inflammation. It may also contain unique qualities that CBD does not, making it suitable for a variety of therapies.

CBDA has anticonvulsant properties and may also be antibacterial, antioxidant, and cancer-preventive (specifically breast cancer). While it is difficult to say which is “better,” there is enough early data to show that CBDA has specific properties that may distinguish it apart from CBD in some areas.


As you can see, CBDA has its own distinct potential in the burgeoning cannabis market. While most of CBDA’s potential is still being researched, there is enough data to offer experts and passionate supplement users hope.

CBDA cannabinoid may be another fantastic alternative to add to your health and wellness regimen for those of you who are just putting your toes into the CBD/health supplement seas. CBDA is regarded to be risk-free, with no high or possible hazards associated with THC (such as if your company drug tests).

Raw CBDA may be just what you need to improve your wellness regimen!

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