CBDP cannabinoid (Cannabidiphorol) is one of over 140 naturally occurring chemical compounds present in cannabis, and it is one of the most understudied and underappreciated cannabinoids currently in existence. Unlike tetrahydrocannabinol (THC) and tetrahydrocannabiphorol, it is a heptyl homolog of cannabidiol (CBD), is non-intoxicating, and does not produce a euphoric high (THCP). CBDP, on the other hand, may be comparable to CBD in that it activates particular receptor types and influences brain chemicals to enhance mood and sleep. Because of these advantages, CBDP may be a psychotropic chemical (without mental or cognitive impairment).
CBDP? What Is It?
CBDP, short for cannabidiphorol and scientifically known as (-)-trans-CBDP, is one of 140 natural chemical compounds (cannabinoids) found in some cannabis strains. It is non-intoxicating and does not provide a euphoric high like CBD, but it has the ability to alter the brain and overall central nervous system by targeting receptor sites such as serotonin and opioid receptors (in theory). CBDP cannabinoid is likely psychoactive due to its receptor targeting.
CBDP has the chemical formula C23H34O2, which means it is made up of 23 carbon atoms, 34 hydrogen atoms, and two oxygen atoms. It likewise has seven carbon atoms on its alkyl side chain, making it a heptyl homologue of cannabidiol. CBD, on the other hand, has five. According to researchers, heptyl cannabinoids with seven-link chains have higher affinity at different receptor sites, as indicated by THCP, which is roughly 30-times more effective than THC at binding to cannabinoid 1 (CB1) receptors.
CBDP is a minor cannabinoid, which means it accounts for less than 1% of the entire cannabinoid profile of a cannabis plant. In comparison, CBD accounts for around 15-20% of a cannabis plant’s total cannabinoid composition.
CBDP was found in 2019 by a group of Italian scientists supported by the UNIHEMP research project. The researchers investigated FM2, a specialized medicinal cannabis cultivar given by the Military Chemical Institute, using sophisticated mass-spectrometry and liquid chromatography to carefully examine the plant materials and determine what’s within. The researchers also discovered THCP, CBDB, and THCB.
CBDP research
CBDP cannabinoid is currently understudied. We know very little about this cannabinoid and how it functions in the human body. CBDP’s pharmacological effects remain unknown even to the research team that found it. However, one recent study investigated how a combination of CBDP and CBD could aid in the treatment of breast cancer. The outcomes are rather intriguing.
CBDP as a possible anti-proliferative agent (breast cancer)
According to a new study released on September 14, 2021, combining CBDP, CBD, and medicines that block enzymes that break down endocannabinoids has anti-proliferative effects.
The researchers observed that both cannabinoids activated catastrophic pathways that caused cancer cell death using human breast carcinoma cells as a model. The capacity to greatly boost reactive oxygen species (ROS) generation, which leads to apoptosis and autophagy, is the most intriguing. Apoptosis and autophagy are the processes that cleanse the body of aberrant cells, which in this case are cancer cells.
The researchers conclude that their findings “mark the first step toward confirming the possible use of these homologs as an addition in anticancer treatment.”
We expect to see additional preclinical or clinical research on CBDP’s anti-proliferative capabilities in the future.
What are the advantages of CBDP?
According to what we know so far, CBDP has therapeutic advantages comparable to CBD and is likely beneficial for anxiety, depression, and stress. CBDP may also help with epilepsy, discomfort, and inflammation.
CBDP shares the same chemical formula & molecular structure as CBD. Because of these similarities, CBDP has a low affinity for cannabinoid 1 (CB1) & cannabinoid 2 (CB2) receptors but operates on other receptor sites to give your body with a variety of advantages.
CBDP, for example, may be beneficial for anxiety, anxiety, and depression. CBD stimulates serotonin (5-HT1A) receptors in the brain. This activation alters how your brain’s serotonin receptors respond to natural serotonin levels in your body. Serotonin, sometimes known as the “bliss molecule,” is an endogenous hormone. Its primary function is to modulate mood and anxiety. CBD’s action at serotonin receptors has been shown in studies to have strong anti-stress and anti-depressant effects. Researchers also believe that CBD’s stimulation of serotonin receptors causes anti-epileptic effects, either completely or partly.
CBDP may also be beneficial for pain and inflammation. Several studies have found that CBD can help with pain symptoms linked with arthritis, fibromyalgia, and multiple sclerosis.
CBDP Effects: How does it make you feel?
CBDP’s effects are unclear, as are the effects of other under-researched small cannabinoids that have not yet been converted into legal goods. There are no anecdotal accounts from CBDP product consumers because they are not widely accessible, at least not in the United States.
CBDP, on the other hand, is almost identical to CBD, but with a seven-alkyl side chain instead of a five-alkyl side chain, implying that CBDP is a potentially stronger, more powerful version of CBD. We may also fairly conclude that CDBP does not produce a euphoric high since it does not connect to CB1 receptors in the same manner as THC, delta-8, or other THC isomer does.
As a result, future CBDP-based medicines may provide the same effects as CBD but with considerably higher strength, suggesting that it might be a viable choice for harder-to-treat conditions such as anxiety, anxiety, and depression.
CBD has the following effects:
- Mental stimulation
- Relaxation
- Calmness
- Mood-enhancement
- Stress relief
- Internal equilibrium
Is it legal to purchase CBDP?
Yes, as far as we know, CBDP cannabinoid is legally lawful and not classified as a controlled substance under the Controlled Substances Act (CSA), providing it is derived naturally from hemp plants containing no more than 0.3 percent THC (or delta-9-thc). When the THC concentration of hemp exceeds 0.3 percent THC, it is deemed marijuana and a federally illegal restricted narcotic. As a result, marijuana-derived CBDP is automatically prohibited under federal law.
How does CBDP differ from CBDA and THCP?
CBDA vs. CBDP
- CBDP and CBDA are cannabidiols from the same plant. CBDA cannabinoid, on the other hand, stands for cannabidiolic acid. One of the primary distinctions between the two cannabinoids is the “acid” component.
- CBDA is mostly found in raw cannabis. Before decarboxylation, it is the acid precursor of CBD. When cannabis is subjected to heat and UV light, it activates CBDA, eliminating its acidic carboxyl group, and converting it to CBD. CBDP formation in the cannabis plant is currently unclear.
- CBDP and CBDA are potentially promising cancer therapies. While CBDA inhibits COX-2 enzymes and slows cancer cell proliferation, the precise anti-cancer actions of CBDP are unclear.
THCP versus CBDP
- CBDP and THCP were discovered simultaneously in 2019. However, we now have a better understanding of THCP’s pharmacological effects and interactions with your endocannabinoid system.
- CBDP and THCP are both heptyl cannabinoids that have quite distinct effects on your body (at least in theory). THCP, like THC, interacts with and binds to cannabinoid receptors in the brain and central nervous system, notably CB1. A high is produced by this CB1 binding action.
- CBDP, on the other hand, is unlikely to connect to cannabinoid receptor types or provide a euphoric high. It very definitely has comparable positive properties as CBD, including as anti-anxiety, anti-inflammation, and anti-pain.
- One of the most striking similarities between CBDP and THCP is the presence of alkyl side chains. Both cannabinoids contain seven-link alkyl side chains, which means they attach to receptors more effectively than THC and CBD, which have five-link side chains.
- Because of its seven-link alkyl side chain, THCP is 33 times more potent at CB1 receptors than THC and 5-10 times more active at CB2.
- We can only assume that CBDP has similarly improved activity by binding at receptor locations because its pharmacological mechanisms are currently being investigated.
Where may CBDP products be purchased?
If you’re looking for CBDP cannabinoid items, we have some terrible news for you. There are currently very few CBDP products available for human or veterinary usage. However, we anticipate an increase of CBDP-based products in the future years.
For the time being, we suggest sticking with hemp-derived CBD products, which are extremely beneficial for anxiety, sadness, pain, inflammation, and sleep, especially if they contain a full-spectrum hemp extract containing 0.3 percent THC.
Conclusion
CBDP is a secret cannabinoid with a lot of power waiting to be unlocked. CBDP cannabinoid, which is comparable to CBD and has an alkyl side chain with seven links, has the potential to outperform CBD by a significant margin. All that remains is for manufacturers to be armed with the required instruments to harness its power and release it into the market. Unfortunately, there are currently relatively few CBDP products available. We await the arrival of new items with bated breath.
